shiga toxin meaning in English
志贺毒素
志贺氏毒素
Examples
- Translocation from endocytic compartments to the cytosol is the essential and rate - limiting step in the intoxication process of most toxins such as ricin , diphtheria toxin , shiga toxin and pseudomonas exotoxin ( pe ) . a number of these toxins are transported to trans - golgi network ( tgn ) , and in many cases such transport to the tgn is required for the translocation and cytotoxicity . in deed , 5 % of the ricin endocytosed by cells has been shown to reach the tgn
蓖麻毒素进入细胞的机理不甚明了，一般认为是rtb先与细胞膜受体结合，主要经过受体介导的内吞作用进入吞噬体，然后沿着内体、高尔基体、内质网等逆向分泌途径，有序地运输到内质网，最后从内质网转位进入细胞浆，在胞浆内攻击核糖体，从而抑制蛋白质的合成，导致细胞死亡。 - To dress the question if other virulence gene were present in this kind of strains , 152 of 436 irp2 - hybridized strains were re - confirmed and selected for this study . the virulence genes or putative virulence genes detected by pcr or hybridization include heat stable toxin ( st ) & heat labile toxin ( lt ) for enterotoxigenic e . coli ( etec ) , invasive plasmid antigen b ( ipab ) for enteroinvasive e . coli ( eiec ) , epec adherence factor ( eaf ) , epec secretion protein c ( espc ) for enteropathogenic e . coli ( epec ) , hemolysin ( hlya ) and shiga toxins ( sltl and slt2 ) for enterohaemorrhagic e . coli ( ehec ) and eaggec probe for entero - aggregative e . coli ( eaggec ) . the prra and yc73 genes of pathogenicity associated island ( pai ) of urepathogenic e . coli ( upec ) and " o " island 28 ( rtx 615 ) gene was also detected , the later was a newly discovered putative pathogenicity island in e . coli o157 : h7
为探讨携带小肠结肠炎耶尔森氏菌的hpi毒力岛的大肠杆菌是否具有其他已知的毒力基因，选取82株由原位杂交和pcr方法初筛irp2阳性的大肠杆菌菌株，进行在致泻性大肠杆菌的25个毒力基因的检测，包括肠产毒性大肠杆菌的热稳定毒素st和热不稳定毒素lt ，肠侵袭性大肠杆菌的侵袭蛋白b基因ipab ，肠致病性大肠杆菌的eaf 、 espc基因，肠出血性大肠杆菌的溶血素hly 、志贺毒素1 ( slt1 ) 、志贺毒素2 ( slt2 )基因，肠集聚性大肠杆菌的eaggec探针，以及在泌尿道致病性大肠杆菌和o157 ： h7大肠杆菌中新发现的毒力岛基因。